Professors Don DeVoe (ME), Cheng Lee (Chem), and Doug English (Chem) will couple multiplexed microfluidics to mass spectrometry for the development of new micro and nanofluidic technology for analyzing proteins in limited biological samples such as human tissue biopsies.
An important early application of the technology will focus on analyzing microdissected tissue from cancer biopsies, leading to the identification of novel protein biomarkers which can be used at the clinical level for early detection, effective diagnostics and prognostics, and treatment selection. In addition, discovered biomarkers may be used by pharmaceutical companies as potential targets for future drug development. Much of the research will take place in the Maryland Microfluidics Laboratory (MML), a new research facility focused on the development of micro/nano fluidic systems for ultrasensitive proteomic analysis, currently under construction in Glenn L. Martin Hall.
February 10, 2006