November 18, 2019 UMD Home FabLab AIMLab


(L-R) Dean Farvardin, Robert W. Deutsch, Jane Brown (of the Deutsch Foundation) and Provost Destler. (Photo by Al Santos)

(L-R) Dean Farvardin, Robert W. Deutsch, Jane Brown (of the Deutsch Foundation) and Provost Destler. (Photo by Al Santos)

 

The Robert W. Deutsch Foundation will give more than $1 million over four years to the University of Maryland's A. James Clark School of Engineering for biological research on the nanoscale.

A cross-disciplinary group of researchers associated with the Clark School is developing a new "biochip" technology that promises to give doctors a new way to discover drugs to treat bacterial infections?without stimulating resistance-building mutations.

The Deutsch Foundation, based in Baltimore, is funding the work in the hope of speeding development of new life-saving drugs and advancing the new field of nano-biotechnology.

"We are very excited and pleased to support this pioneering research, which represents the enormous potential in the merging of biology and nanotechnology," says Robert W. Deutsch, foundation president. "We believe that practical applications of this research could become the source of future innovations."

Deutsch will participate in an agreement-signing ceremony at the Clark School's Kim Engineering Building later today.

Controlling Biology at the Nanoscale: Next Generation BioChips for Drug Discovery

Anthrax, tuberculosis, meningitis and pneumonia are all caused by bacteria and treated through the use of antibiotics. But bacteria can mutate, and develop resistance to the antibiotics?even to vancomycin, the most potent antibiotic currently available to doctors.

University of Maryland researchers?from the Clark School and the University of Maryland Biotechnology Institute in College Park and the School of Pharmacy in Baltimore?are developing a nanoscale, microfluidic biochip that can serve as a tiny drug discovery laboratory. The chip can, in effect, serve as a miniature test subject?accepting a drug and reporting back on how it performs.

The Deutsch Foundation is funding a specific biochip research program designed to complete the group's work and demonstrate its usefulness. The program will investigate biochips that address quorum-sensing bacteria, or bacteria that gather in an area of the body and signal each other until there are enough bacteria gathered to mount an attack. If a drug is found that can block the bacteria from signaling each other, the attack can be prevented.

The biochip can be used as a testbed for such drugs?drugs that the bacteria won't be able to develop a resistance to, unlike antibiotics. Success for this application could have widespread implications for testing drugs for a wide range of health problems.

The Clark School's William Bentley (bioengineering), Reza Ghodssi (electrical and computer engineering [ECE], Institute for Systems Research[ISR] and Maryland NanoCenter) and Gary Rubloff (Maryland NanoCenter, materials science and engineering, ECE and ISR) are involved in this research.

Clark School press release.



Related Articles:
Maryland Exchange with Italian University Boosts Research on Artificial Cells
New Advance in Biochip Research
Ghodssi, Rubloff part of $2 million NSF grant
"Side Effects May Not Include?"

August 31, 2006


«Previous Story  

 

 

"We are very excited and pleased to support this pioneering research, which represents the enormous potential in the merging of biology and nanotechnology."

Robert W. Deutsch

Current Headlines

ChBE Ph.D. Student Wins Battery500 Young Investigators Award

Clark School Professor Elected 2019 APS Fellows

UMD Graduate Student Kang-Yi Lin Receives 2019 ALD/ALE Award

NSF Awards $1M Grant to UMD Researchers

Ghodssi Receives Senior Faculty Outstanding Research Award

University of Maryland Launches Quantum Technology Center

Mapping Nucleation Kinetics with Nanometer Resolution

MEI² Receives Two New Innovative Vehicle Technology Awards

UMD Hosts 4th Annual Machine Learning Bootcamp and Workshop

UMD Alumna Receives PECASE Award, Highest Honor Given by U.S. Government to Early Career Scientists

 

Colleges A. James Clark School of Engineering
The College of Computer, Mathematical, and Natural Sciences

Communicate Contact Us
Contact the Webmaster
Google+
Follow us on TwitterTwitter logo

Links Privacy Policy
Sitemap
RSS

Copyright The University of Maryland University of Maryland
2004-2019